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Kisspeptin-10

Description

Kisspeptin‑10 emerges as a promising peptide in endocrine and reproductive research. Acting on hypothalamic–pituitary–gonadal pathways under investigation, it supports optimal GnRH stimulation, gonadotropin release, and systemic resilience. By modulating kisspeptin receptor activity and promoting adaptive regulation, Kisspeptin‑10 contributes to improved reproductive function, balanced endocrine performance, and protection against stress‑induced dysregulation.

Additional Information

  • Weight: 0.08 lbs

  • Dimensions: 0.87 × 1.18 × 0.87 in

  • Size: 5mg, 10mg

This product is intended solely for research purposes. It is not authorized for use in humans or animals and should only be handled by trained personnel in appropriate laboratory settings.

Highlights

Biochemical Profile

  • Stability :Stable lyophilized, refrigerated.

  • Solubility: Readily soluble in water and physiological saline

  • Storage Conditions: Store at 36‑46 °F (2‑8 °C)

  • Form: White to off‑white crystalline powder

Structural Properties

  • Amino acid sequence: Tyr‑Asn‑Trp‑Asn‑Ser‑Phe‑Gly‑Leu‑Arg‑Phe

  • Molecular Mass: ~1302.5 g/mol

  • Composition: C₆₄H₈₄N₁₆O₁₂

  • Architecture: Linear decapeptide (10 amino acids)

Biological Mechanism

Kisspeptin‑10 functions as a synthetic decapeptide (Tyr‑Asn‑Trp‑Asn‑Ser‑Phe‑Gly‑Leu‑Arg‑Phe), engaging hypothalamic–pituitary–gonadal regulatory pathways to support endocrine resilience and optimize reproductive performance.

Key Mechanisms

GnRH Stimulation
Activates hypothalamic pathways to trigger gonadotropin‑releasing hormone secretion, reinforcing reproductive signaling.

Reproductive Adaptation
Supports fertility optimization and adaptive reproductive function under stress or age‑related decline.

Hormonal Modulation
Balances gonadotropin release, contributing to stable endocrine performance and systemic resilience.

Systemic Integration
Coordinates kisspeptin receptor activity with broader endocrine networks, sustaining metabolic and reproductive harmony.

Metabolic Benefits

Hormonal Energy Dynamics
Supports efficient endocrine signaling through kisspeptin‑mediated GnRH activation, sustaining systemic vitality.

Nutrient Utilization
Enhances uptake and distribution of essential substrates in reproductive and endocrine tissues.

Oxygen Efficiency
Promotes improved oxygen delivery and utilization within hormone‑responsive cells, reinforcing resilience under stress.

Adaptive Recovery
Stabilizes metabolic pathways that contribute to repair and regulation during age‑related or environmental challenges.

Research Highlights

KissPetin-10 demonstrates strong tolerability in investigative research settings, with only mild and short‑lived effects occasionally observed.

Endocrine Regulation

Investigations highlight Kisspeptin‑10’s role in stimulating GnRH release, reinforcing hormonal balance and reproductive signaling.

Reproductive Function

Preclinical studies suggest enhanced gonadotropin secretion and adaptive fertility support under stress or age‑related decline.

Stress Adaptation

Research indicates modulation of hypothalamic–pituitary–gonadal pathways, contributing to resilience against systemic and environmental stressors.

Systemic Integration

Findings show improved coordination of kisspeptin receptor activity with broader endocrine networks, supporting metabolic stability and regenerative adaptation.

Possible Research-Related Effects

KissPetin-10 exhibits favorable tolerability in research contexts, with minor and short‑duration effects occasionally reported:

Favorable Tolerability

Kisspeptin‑10 demonstrates strong tolerability in investigative research settings, with only mild and short‑lived effects occasionally observed

Transient Flushing

Brief localized sensations sometimes noted in endocrine or reproductive regions, typically resolving without intervention.

Low-grade Fatigue

Mild tiredness reported in select studies, subsiding spontaneously.

Hormonal Sensitivity

Occasional temporary shifts in comfort or regulatory balance during adaptive endocrine phases.

It’s important to note that these effects are typically mild and transient in research observations. However, comprehensive long-term safety data is still being collected.

Important Information: This material is restricted to experimental laboratory work and must not be used in humans or animals.

References

Kisspeptin‑10 Overview, Dosing & Safety. Peptide Database, 2024. — Editorial Team.

​Kisspeptin‑10 Technical Specification Sheet. Peptide Biologix, 2024. — Research Monograph.

​TARGET DOSSIER: Kisspeptin‑10. Peptide Recon, 2025. — Peptide Reconnaissance Division.

​Kisspeptin‑10 Peptide: Endocrine and Reproductive Research Pathways. Biolongevity Labs, 2025. — Editorial Team, reviewed by Ky H. Le.

​Kisspeptin‑10 Peptide: Potential Roles in Hormonal Regulation and Fertility Adaptation. Resident Resource Guide, 2024. — Resident Contributor.

​Kisspeptin‑10 Peptide: Insights into Stress Response and Endocrine Repair. Atlas of Science, 2023. — Editorial Team.

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