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Pinealon
PINEALON
$45.00
PINEALON
Quantity
Description
Pinealon is a synthetic tripeptide that provides a focused pathway for modulating neuronal activity. Composed of glutamic acid, aspartic acid, and arginine, Pinealon’s linear structure allows for selective regulation of intracellular signaling processes, making it especially relevant in studies of cognitive function and neuroprotection. This receptor and pathway specificity has positioned Pinealon as a reference compound in gerontological and neurological research, serving as a model for exploring mechanisms of memory support, oxidative stress reduction, and cellular resilience. Beyond its role in brain function, ongoing investigations suggest Pinealon may contribute to anti‑aging strategies and offer protective effects in conditions linked to neurodegeneration.
Additional Information
Weight: 0.08 lbs
Dimensions: 0.87 × 1.18 × 0.87 in
Size: 5mg, 10mg
This product is intended solely for research purposes. It is not authorized for use in humans or animals and should only be handled by trained personnel in appropriate laboratory settings.
Highlights
Structural Properties
Selectivity: Regulates neuronal signaling
Solubility: Water‑soluble, may need gentle warming
Storage Conditions: Store frozen at −20 °C to −80 °C
Form: White to off‑white solid
Biochemical Profile
Chemical Formula: C₁₅H₂₆N₆O₈
Molecular Weight: 418.4 g/mol
CAS: 175175‑23‑2
Structure: Linear tripeptide composed of Glu‑Asp‑Arg
Biological Mechanism
Pinealon is a synthetic tripeptide studied for its neuroprotective activity, supporting cognitive function, oxidative stress defense, and potential anti-aging effects
Key Mechanisms
Memory Enhancement
• May improve short‑term and working memory through synaptic support and neurochemical balance.
Stress Adaptation
• Contributes to cellular resilience under oxidative and metabolic stress conditions.
Age‑Related Decline Mitigation
• Supports brain function and structural integrity in aging models.
Metabolic Benefits
Gene Activity Modulation
• Influences expression of genes linked to neuroinflammation and cellular stress response.
Support for Vascular Health
• May assist microcirculation and promote nutrient delivery in neural tissues.
Tissue Recovery
• Encourages repair and structural integrity in aging or stressed brain regions.
Research Highlights
Research on Pinealon has uncovered a wide range of potential applications beyond its role in cognitive support:
Neuroprotective Research
Main focus on cognitive resilience:
• Enhances synaptic signaling and memory formation
• Shields neurons from oxidative damage
• Reduces neuroinflammatory markers in aging models
• Shows promise in neurodegenerative and post‑stroke recovery studies
Anti-Stress Properties
Emerging cellular defense activity:
• Lowers oxidative stress and supports mitochondrial stability
• Modulates ERK 1/2 and related survival pathways
• Improves outcomes in models of emotional and metabolic stress
• Potential applications in age‑related cognitive decline
Regenerative Insights
Unexpected effects in brain tissue repair:
• Promotes structural recovery in damaged neural regions
• Encourages cellular regeneration and plasticity
• Supports vascular health and nutrient delivery
• Investigated for roles in long‑term brain maintenance
Clinical Research Directions
Translational applications under study:
• Trials in age‑related memory loss and cognitive fatigue
• Research on neuroprotection in ischemic models
• Investigations into oxidative stress modulation
• Studies on peptide‑based brain support therapies
Possible Research-Related Effects
Pinealon has generally shown a strong safety profile due to its targeted action on neuronal pathways and low systemic reactivity:
Mood Elevation
Some participants reported improved emotional tone and reduced mental fatigue.
Increased Focus
Enhanced concentration and task engagement observed in cognitive performance studies.
Sleep Quality Changes
Reports of deeper sleep and altered REM patterns in long‑term use.
Thermal Sensations
Occasional mild warmth or chill perception during initial administration.
Its selectivity for neuronal signaling pathways helps reduce off‑target effects commonly associated with broader neuroactive peptides.
Important Information: This material is restricted to experimental laboratory work and must not be used in humans or animals.
References
Peptide Pinealon regulates gene expression and protein synthesis in cell cultures under oxidative stress. Bull Exp Biol Med, 2016.
Short peptides regulate expression of genes involved in neurogenesis and apoptosis. Neurochem J, 2015.
Pinealon increases viability of neuronal cultures under hypoxia and oxidative stress. Adv Gerontol, 2014.
Tripeptide Pinealon modulates circadian rhythms and improves memory in animal models. Biogerontology, 2013.
Peptide bioregulators in aging: Pinealon as a neuroprotective agent. Front Aging Neurosci, 2012.
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