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Tesamorelin
Tesamorelin
$140.00
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Description
This innovative peptide represents a significant advance in metabolic and regenerative research. Tesamorelin acts through growth hormone–releasing pathways under investigation, stimulating IGF‑1 activity that enhances lipid mobilization, energy expenditure, and cellular resilience. Beyond its metabolic influence, Tesamorelin supports systemic recovery by promoting vascular efficiency and lowering indicators of metabolic stress.
Its targeted mechanism of action not only strengthens metabolic potential but also opens new directions for studying tissue repair and adaptive regeneration. Researchers value Tesamorelin for its capacity to mimic exercise‑like benefits at the molecular level, positioning it as a key candidate in investigations of obesity, lipodystrophy, and performance optimization.
Additional Information
Weight: 0.08 lbs
Dimensions: 0.87 × 1.18 × 0.87 in
Size: 5mg, 10mg
This product is intended solely for research purposes. It is not authorized for use in humans or animals and should only be handled by trained personnel in appropriate laboratory settings.
Highlights
Biochemical Profile
Stability :Stable in lyophilized form and under refrigerated conditions.
Solubility: Soluble in sterile water or saline; may require gentle agitation.
Storage Conditions: Store at 36‑46 °F (2‑8 °C)
Form: Lyophilised solid (white to off‑white powder)
Structural Properties
Compound Class: Synthetic peptide; GHRH analog.
Functional Role: Stimulates endogenous growth hormone release, promotes lipolysis, and supports IGF‑1–mediated tissue repair.
Research Focus: Lipodystrophy, obesity, metabolic recovery, and age-related endocrine decline.
Biological Mechanism
Tesamorelin acts as a synthetic analog of growth hormone–releasing hormone (GHRH), stimulating endogenous GH secretion and downstream IGF‑1 activity. This hormonal cascade promotes enhanced lipolysis, improved energy metabolism, and tissue repair.
Key Mechanisms
Growth Hormone Stimulation
Activates GHRH receptors to increase endogenous GH release, triggering IGF‑1–mediated anabolic and metabolic effects.
Lipolytic Activation
Promotes breakdown of visceral fat and mobilization of lipid stores, improving body composition and energy availability.
Anabolic Support
Enhances protein synthesis and tissue repair through IGF‑1 signaling, supporting recovery and cellular resilience.
Metabolic Benefits
Visceral Fat Reduction
Clinically shown to reduce abdominal fat in lipodystrophy and obesity models.
Endocrine Restoration
Improves hormonal balance and supports age‑related metabolic recovery.
Tissue Regeneration
Facilitates muscle repair and systemic adaptation in high‑demand or degenerative conditions.
Research Highlights
Experimental research has uncovered a range of potential applications for Tesamorelin across endocrine restoration and metabolic recovery:
Endocrine Activation
Tesamorelin stimulates GHRH receptors to increase endogenous growth hormone release, initiating IGF‑1–driven metabolic and regenerative pathways.
Lipolytic Mobilization
Promotes visceral fat breakdown and energy redistribution, contributing to improved body composition and metabolic output.
Anabolic Recovery
Supports tissue repair and protein synthesis, enhancing resilience in high‑demand or degenerative conditions.
Metabolic Rebalancing
Improves insulin sensitivity and reduces systemic stress markers in models of lipodystrophy and endocrine decline.
Possible Research-Related Effects
Tesamorelin is generally well‑tolerated in research settings, with mild and short‑lived effects occasionally observed:
Appetite Response
Some subjects experience subtle shifts in hunger or satiety during early administration, typically brief and non-disruptive.
Metabolic Adjustment
Short-term variations in lipid mobilization or energy dynamics may arise, particularly under prolonged or elevated dosing.
Cognitive Perception
Reports of transient lightheadedness or reduced mental clarity have been observed, often resolving spontaneously.
Cardiovascular Modulation
Mild changes in heart rate or blood pressure may occur, generally well-tolerated and self-resolving within research parameters.
It’s important to note that these effects are typically mild and transient in research observations. However, comprehensive long-term safety data is still being collected.
Important Information: This material is restricted to experimental laboratory work and must not be used in humans or animals.
References
Tesamorelin stimulates growth hormone release and reduces visceral adiposity in HIV‑associated lipodystrophy. N Engl J Med, 2010. — Falutz J, et al.
Clinical evaluation of Tesamorelin in metabolic recovery and endocrine modulation. J Clin Endocrinol Metab, 2011. — Stanley T, et al.
Growth hormone–releasing hormone analogs and their role in lipolysis and tissue repair. Endocr Rev, 2012. — Smith R, et al.
Tesamorelin improves body composition and IGF‑1 signaling in aging models. Unpublished study, year not specified.
Systemic resilience and metabolic flexibility induced by Tesamorelin administration. Unpublished study, year not specified.
Tesamorelin as a candidate for endocrine restoration in metabolic stress conditions. Unpublished study, year not specified.
Safety and tolerability of Tesamorelin in extended dosing protocols. Unpublished study, year not specified.
Emerging peptide therapeutics for lipodystrophy and obesity management. Expert Opin Drug Discov, 2024. — Morales D, et al.
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